Ketamine Assisted Psychotherapy as an Approach to Mental Healing

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Ketamine assisted psychotherapy (KAP) is emerging as a promising alternative for individuals struggling with various mental health conditions. Mental health issues have become increasingly widespread in our fast-paced, modern world, leading to a growing demand for innovative approaches to treatment. 

In this article, we’ll delve into what KAP is, how it works, what to expect during treatment, how to determine if it’s the right choice for you, and conclude by exploring its potential impact on mental healing. 

What Is Ketamine Assisted Psychotherapy?

Ketamine assisted psychotherapy (KAP) is an integrative therapeutic approach that combines the administration of the dissociative anesthetic, ketamine, with psychotherapy. It is primarily used to address a range of mental health ailments, including depression, anxiety, post-traumatic stress disorder (PTSD), and more. KAP is distinct from traditional pharmacotherapy due to its emphasis on combining the psychoactive properties of ketamine with talk therapy, enabling a holistic approach to mental healing.

How Does KAP Work for Mental Health?

Ketamine assisted psychotherapy offers a novel approach to treating mental health disorders, and its mechanism of action is complex but promising. Ketamine primarily works by blocking NMDA receptors, ultimately affecting glutamate release, a neurotransmitter crucial for information processing and forming neural connections. The resulting increase in brain-derived neurotrophic factor (BDNF) levels promotes neuron and synapse growth, potentially counteracting the effects of mental health disorders. Ketamine may also reduce brain inflammation, offering relief from symptoms like anxiety and depression.

Research has lent support to the efficacy of ketamine-assisted psychotherapy. Studies, such as one in JAMA Psychiatry (2018), demonstrated significant improvements in depression with ketamine-assisted therapy compared to a placebo group. Similarly, a study in the Journal of Psychopharmacology (2019) indicated its effectiveness in reducing PTSD symptoms in veterans. 

Long-term effects have been observed, as evidenced by a study in the Journal of Affective Disorders (2021) that reported sustained improvements in mood and cognitive function three months post-treatment for depression. Additionally, a study in the Journal of Clinical Psychopharmacology (2018) highlighted its ability to reduce alcohol cravings and relapse frequencies in patients with alcohol use disorder.

What to Expect During Treatment

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During a ketamine assisted psychotherapy session, patients can expect a unique and non-traditional therapeutic experience. Here’s a step-by-step guide to what they can anticipate:

Initial Consultation

Before the treatment session, patients will have an initial consultation with their therapist. During this meeting, they will discuss their mental health history and current symptoms. Additionally, the therapist will offer specific guidance on how to prepare for the upcoming ketamine infusion, including dietary restrictions and potential adjustments to their medication regimen.

Ketamine Administration

Ketamine is typically administered through an intravenous (IV) infusion in a comfortable and private setting. Throughout this process, patients receive close monitoring from healthcare professionals to ensure their safety and overall well-being.

Altered State of Consciousness

With the onset of ketamine’s effects, patients may undergo an altered state of consciousness that distinctly sets this therapy apart from conventional talk therapy. Some individuals may describe sensations such as detachment from their physical body or an elevated awareness of their thoughts and emotions.

Therapeutic Exploration

While in this altered state of consciousness, patients collaborate with their therapist to delve into their thoughts, emotions, and behaviors. Various techniques may be employed by the therapist to aid in this exploration, including guided imagery, music therapy, and mindfulness practices.


Following the ketamine infusion, patients typically spend some time in repose, reflecting on their experiences. Subsequently, the therapist and patient work together to integrate the insights gained during the session into their daily lives. This includes the development of coping strategies for effectively managing their symptoms.

How to Know if This Treatment Is for You?

Determining if ketamine-assisted psychotherapy is the right treatment for you involves careful consideration and consultation with a qualified mental health professional. Here are some steps to help you assess whether this treatment is a suitable option for your specific situation:

Consult with a Mental Health Professional

The first and most crucial step is to consult with a mental health expert who is experienced in administering ketamine-assisted psychotherapy. They can assess your unique mental health needs and provide guidance based on their expertise. The Substance Abuse and Mental Health Services Administration (SAMHSA), a U.S. authority on mental health and substance abuse, can provide valuable resources and information to help you locate qualified professionals in your area.

Evaluate Your Mental Health Condition

Consider your current mental health condition. KAP may be a viable option if you are struggling with treatment-resistant depression, anxiety, PTSD, or addiction. It’s important to discuss the severity and duration of your symptoms with your mental health provider.

Desire for an Alternative Approach

If you’re open to exploring innovative treatment options and have not found relief through traditional talk therapy or medication, ketamine-assisted psychotherapy may be worth considering.

Willingness for Intense Experiences

Ketamine sessions can be intense and may induce hallucinatory or transformative experiences. Assess your readiness for such experiences, as they are a fundamental part of the therapy process.

Lack of Other Viable Options

If you have exhausted conventional treatment options without significant improvement, ketamine-assisted psychotherapy could be an option to explore.

Consider Substance Abuse and Medical History

Individuals with a history of substance abuse or habit may not be suitable candidates for ketamine therapy due to the potential for ketamine abuse and habit-forming nature. Discuss your substance use history with your mental health clinician. Additionally, some medical conditions or medications may contraindicate ketamine therapy, so disclose your medical history and current medications.

Discuss Potential Risks and Benefits

Your mental health professional will discuss the potential risks and benefits associated with KAP. Make sure to have a thorough conversation about what you can expect from the treatment, including possible side effects.


Ketamine assisted psychotherapy offers a promising avenue for mental healing, showcasing the potential for rapid relief from debilitating mental health conditions. The synergy between ketamine and psychotherapy can open doors to self-discovery, emotional healing, and personal growth. However, it’s essential to approach this treatment with a thorough understanding of its mechanisms and a professional evaluation of its suitability for your unique circumstances. 

At Sunshine Infusion, we offer ketamine treatment that can potentially transform your mental health journey. If you’re seeking an innovative and holistic approach to mental healing, don’t hesitate to contact us today. Our experienced team is here to support you on your path to recovery.

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